http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006084622-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afbf2d47b53385e0171387ee8d1496a6 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2005-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1be4ba5997d7afa104bf87087beda298 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_033aa4a2dfe12c71e5b2ee6b94bc96ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44291bb989e762e3bc408f434cae0492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_489da6ee068f1fcbec993cbbd812d1fd |
| publicationDate | 2006-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2006084622-A1 |
| titleOfInvention | Angiogenic factor and use thereof in treating cardiovascular disease |
| abstract | The present invention relates to a novel VEGF protein product, and nucleic acid encoding the novel protein product, comprising exons 1-6 and 8 of the VEGF gene, and its use thereof in treating the cardiovascular system and its diseases through effects on anatomy, conduit function, and permeability. VEGF 145 has been found to be an active mitogen for vascular endothelial cells and to function as an angiogenic factor in-vivo. VEGF 145 has novel properties compared with previously characterized VEGF species with respect to cellular distribution, susceptibility to oxidative damage, and extra-cellular matrix (ECM) binding ability. The present invention provides methods of treating the cardiovascular system, enhancing endothelialization of diseased vessels, and enhancing drug permeation by providing the novel VEGF protein product. The invention also provides expression vectors, compositions, and kits for use in the methods of the invention. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115151262-A |
| priorityDate | 1998-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 347.