| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34cd20c171d27cfc98de08d1eb461a3a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54306 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-537 |
| filingDate |
2004-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cae1be619277d95ca54463c6524e43f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_883fce51dc48ff4ad66c057d7e74645f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59b48d53f42f1b456e1811bb8cc91391 |
| publicationDate |
2006-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006073534-A1 |
| titleOfInvention |
Method for cleaving and deglycosylating antibodies to promote ligand binding |
| abstract |
The present invention details methods to detect glycoproteins in samples to identify a disease state. In particular, an improved sandwich assay is described, using both an antibody and an array of lectins. Methods for increasing the efficiency of interaction of an antibody with a ligand by cleaving the antibody to remove the carbohydrate moiety, and orienting the cleaved fragment on a matrix to enhance recognition of a ligand are also described. Methods of differentiating pregnancy-derived and disease derived samples are also described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005026866-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10697982-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10697983-B2 |
| priorityDate |
2004-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |