| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ebb6a553affdc364c91cffe3baf12564 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-455
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-455 |
| filingDate |
2005-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d0125cef1346a79c853be0aceea94ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d9a618d5a821427ddab33b04ef0cf44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c11039812a615ddce1601c6db8de6d4e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2570465457b706836e33a112c967e59 |
| publicationDate |
2006-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006030602-A1 |
| titleOfInvention |
(S)-amlodipine malate |
| abstract |
One aspect of the present invention relates to optically pure (S)-amlodipine malate. Another aspect of the present invention relates to (rac)-amlodipine malate. In a preferred embodiment, the compound is optically pure (S)-amlodipine L-malate. Another aspect of the present invention relates to a pharmaceutical composition comprising optically pure (S)-amlodipine malate. Another aspect of the present invention relates to a method of preparing optically pure (S)-amlodipine malate, comprising admixing optically pure (S)-amlodipine with malic acid. Another aspect of the present invention relates to the various polymorphic and solvated forms of optically pure (S)-amlodipine malate. In another prefered embodiment the invention relates to polymorphic and solvated forms A-G. The present invention also relates to a method of preparing optically pure (S)-amlodipine malate, comprising combining a salt of optically pure (S)-amlodipine with a malate salt to give optically pure (S)-amlodipine malate. In a preferred embodiment, the malate salt is an optically pure L-malate salt. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11471409-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019314279-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10959991-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10952998-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019200143-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112334134-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11364230-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10799453-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10894039-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018067959-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10695329-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3522872-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11701326-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11484498-B2 |
| priorityDate |
2004-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |