http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006019908-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81075572b8d1526ce20dbf5dd7dbded8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7052 |
filingDate | 2005-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3e6f9dea1ceb9dbef7a4db3c3c6733e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9ca19618f2501077da2506c57dad7d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19641ea3c10f571af3918d914cb41f88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3c50fbc4323412eb74d847c185dca7c |
publicationDate | 2006-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2006019908-A1 |
titleOfInvention | Process for the preparation of azithromycin monohydrate isopropanol clathrate |
abstract | The present invention relates to an improved, cost effective and easy process for the preparation of azithromycin monohydrate isopropanol clathrate. The process provides a one-step method of preparing azithromycin monohydrate isopropanol clathrate directly from 9-deoxo-9a-aza-9a-homoerythromycin A. The process comprises at least partial dissolution and/or suspension of 9-deoxo-9a-aza-9a homoerythromycin A in isopropanol to form a mixture, adding methylating solution to the said mixture, refluxing or heating said mixture to form a reaction mixture, adding alkaline solution to the reaction mixture to adjust pH from about 10 to about 11 and isolating pure azithromycin monohydrate isopropanol clathrate. The process helps in reducing the total time of preparation, total utility cost for the production and also helps to avoid handling loss. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7851454-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009018090-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003139583-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7414114-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009010938-A1 |
priorityDate | 2004-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.