| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_08e05b0b33b64adc7b87382801ba40b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9284e6599c8ddde900744edd6d9e8545 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-355
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 |
| filingDate |
2004-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6b840a89ba28cc32f336e2d495fbcaf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa80859c46c286ec91e340839883ed69 |
| publicationDate |
2006-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006014763-A1 |
| titleOfInvention |
Methods for altering mRNA splicing and treating familial dysautonomia and other mechanistically related disorders |
| abstract |
This invention relates to methods for altering the splicing of mRNA in cells. In particular, this invention also relates to methods for increasing the ratio of wild type to misspliced forms of mRNA and corresponding encoded proteins in cells possessing a mutant gene encoding either the i) misspliced mRNA corresponding to the mutant protein or ii) a component in the splicing machinery responsible for processing the misspliced mRNA. In addition, this invention relates to treating individuals having a disorder associated with a misspliced mRNA, such as Familial Dysautonomia or Neurofibromatosis 1, by administering to such an individual a cytokinin such as kinetin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9879014-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2015005491-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010234402-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015005491-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008150509-A1 |
| priorityDate |
2003-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |