| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f221ff601a630ca8afbb9d3a6a30d3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7b424fac81df3a59a240e10ce25043f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4207bffa296c39b1619ebfb1287f98ea |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-858
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43518 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 |
| filingDate |
2005-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03cb67ce1c917b62e9fc305189a80632
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c4ffef743c8da8d645ff928513cfc05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e67eb8d331b8725a27013cec38f9a331 |
| publicationDate |
2006-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006014691-A1 |
| titleOfInvention |
Mechanically activated channel blocker |
| abstract |
The present invention discloses a peptide of SEQ ID NO:1 and its variants that blocks stretch-activated ion channels. All amino acids in this peptide are D-amino acids. The peptide, designated as D-GsMTx4, is an enantiomer of a peptide GsMTX-4 present in the venom of the spider Grammostola spatulata . The present invention also discloses a method for inhibition of stretch activated ion channels in a cell. This peptide can be used for the treatment of cardiac arrhythmias and other pathologies that involve alteartions in mechanical stress. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018103761-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112516284-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018108185-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106432422-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015134964-A1 |
| priorityDate |
2004-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |