Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5c5e982732ef01c15fda274078dc4b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82e484e177965d07d1c3e3cc6c793fec |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1892 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 |
filingDate |
2003-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e6d9d7092f90acaee5156a8186fbfc7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42bfa0b7f9393fb2df029fa2c53eb811 |
publicationDate |
2006-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2006009442-A1 |
titleOfInvention |
Process for producing carbapenem compound for oral administration |
abstract |
The present invention provides a process for efficiently producing a 1β-methylcarbapenem compound for oral administration. The process, which is for producing a 1β-methylcarbapenem compound represented by general formula (2), is characterized by reacting a β-lactam compound represented by general formula (1) as a starting material with a thiol compound (R 3 —SH) in the presence of a base and optionally eliminating the protective group R 1 . n n nIn the formulae (1) and (2), R 1 denotes a hydrogen atom, a trimethylsilyl group or a triethylsilyl group; R 2 denotes an alkyl group having 1 to 10 carbon atoms or a cycloalkyl group having 3 to 10 carbon atoms; R 3 denotes an organic group; and R 4 denotes hydrogen, a trimethylsilyl group or a triethylsilyl group. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7538212-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006252929-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103012406-A |
priorityDate |
2002-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |