| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_082507838ffd3a482218a2d116731fbd |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D11-0407
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D11-0403
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D11-0484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D11-0411 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate |
2005-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b2b745b216de933e5ed81b50d1d6b69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d59d26afd4203840ad6a51f859461a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e65aafc3d9b9aabd58c467f5858d939e |
| publicationDate |
2006-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2006008531-A1 |
| titleOfInvention |
Method for producing solid-lipid composite drug particles |
| abstract |
A method of producing solid composite lipid/drug nanoparticles that includes the steps of: (1) dissolving a lipid and a drug in a suitable organic solvent to form a solution; (2) emulsifying the solution in a liquid to form an emulsion having a discontinuous phase of micelles comprising the organic solvent, the drug and the lipid, and a continuous phase comprising the liquid; and (3) contacting the emulsion with a supercritical fluid under conditions suitable to keep the supercritical fluid in a supercritical state, whereby the supercritical fluid extracts the organic solvent from the micelles, causing them to precipitate as organic-solvent free solid composite lipid/drug nanoparticles suspended or dispersed in the liquid. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9226900-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005084533-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011172141-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7595348-B2 |
| priorityDate |
2003-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |