http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005287524-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a0e7de35c3750b3f1dbb7a1804fc801 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c6d506293720d79d9b9c1500cc403cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a7312f8bea29633e9cd2e3f3f7a3be2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-20 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
| filingDate | 2005-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46477ffbc62d077a22fcb7b0d935108b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb6e2eb7a7196393b5b5d415b148b278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8653c10207a8778af02c30de7d9ac8f7 |
| publicationDate | 2005-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2005287524-A1 |
| titleOfInvention | Differential serological diagnosis of equine infectious anemia virus infected and vaccinated horses using recombinant S2 protein |
| abstract | We describe here the development and optimization of an embodiment of a new serologic EIAV diagnostic ELISA assay to detect serum antibodies to the EIAV S2 protein that are produced in infected horses, but not in horses inoculated with the EIAV UK ΔS2 vaccine virus. An embodiment of the test S2 protein antigen was developed using the S2 gene sequence from the EIAV UK strain of virus and a series of modifications to facilitate production and purification of the diagnostic antigen, designated HS2G. Using this embodiment of an HS2G as antigen, we describe the development of an affinity ELISA (NN-ELISA) that provides a sensitive and specific detection of S2-specific serum antibodies in experimentally and field infected horses (22/24), without detectable reactivity with immune serum from uninfected (12/12) or vaccinated (29/29) horses. |
| priorityDate | 2000-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.