http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005272747-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 |
| filingDate | 2005-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09ba0f901eb42de5322a0805fdd5e6a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_281cde49fa161f70b5acea5757e02bba |
| publicationDate | 2005-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2005272747-A1 |
| titleOfInvention | Preparation of triazoles by organometallic addition to ketones and intermediates therefor |
| abstract | The invention provides a process for the preparation of a compound of the formula: n nor an acid addition or base salt thereof, wherein R is phenyl optionally substituted by 1 to 3 substituents each independently selected from halo and trifluoromethyl; n R 1 is C 1 -C 6 alkyl; and “Het” is pyrimidinyl optionally substituted by 1 to 3 substituents each independently selected from C 1 -C 4 alkyl, C 1 -C 4 alkoxy, halo, oxo, benzyl and benzyloxy, n ncomprising reaction of a compound of the formula: n n nwherein R is as previously defined for a compound of the formula (I), with a compound of the formula: n n nwherein R 1 and “Het” are as previously defined for a compound of the formula (I) and X is chloro, bromo or iodo, in the presence of zinc, iodine and/or a Lewis acid and an aprotic organic solvent: said process being optionally followed by conversion of the compound of the formula (I) to an acid addition or base salt thereof. |
| priorityDate | 1996-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 357.