| abstract |
The present disclosure provides a method for detecting a protease, which is simple, sensitive, and capable of high throughput. The method detects a protease in a sample by measuring lysis of a liposome due to activation of a modified or inactive channel-forming agent. Also disclosed is a method for screening a test compound, to determine if the test compound can function as protease inhibitor. A method for identifying a protease cleavage site is also disclosed. |