| abstract |
The invention provides a human NPFF2 which is associated with the hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD and asthma, and genito-urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, respiratory diseases like COPD and asthma, and genito-urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of NPFF2 as well as pharmaceutical compositions comprising such compounds. |