| abstract |
The invention relates to new competitive inhibitors of trypsin-like serine proteases, their synthesis, pharmaceutical compositions containing the compounds as active ingredients, and the use of the compounds as thrombin inhibitors, anticoagulants and antiinflammatory inhibitors for prophylaxis and treatment of related diseases, according to the formula n n nwherein A 1 represents a structural fragment of formulas n n nA 2 represent a structural fragment of formulas n n nB represents a structural fragment of formulas n nFurther described is novel compounds, the new use of compounds and especially new structural fragment in synthesis of pharmaceutical compounds. |