abstract |
The need for new class of antifungal drugs with high efficacy, low toxicity and novel mode of action is well established. Synthesis and antifungal activity of bile acid derived new steroidal dimers N 1 ,N 3 -Diethylenetriamine bis [cholic acid amide] (1) and N 1 ,N 3 -Diethylenetriamine bis [deoxycholic acid amide] (2) having novel amphiphile topology is described. |