| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc905cbef116a1ec61d12125af9427f3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-22 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-678
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-553 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-67 |
| filingDate |
2004-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e58a1d3104afe527b49059a9b447c304
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed93c3fe457af04eac9518756caa27e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94c4842bd4504ad98502e96f948ebefd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9011bacdf1995fea22f0db2d6577fa58 |
| publicationDate |
2005-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005214357-A1 |
| titleOfInvention |
Liposome and preparation method of the same |
| abstract |
The present invention relates to a composition and a method for preparing a liposome, the liposome including a lipid bilayer and an aqueous core contains a hydrophobic or a hydrophilic drug and a component—Vitamin E derivative (d-α tocopheryl polyethylene glycol 1000 succinate; TPGS). TPGS is able to increase the encapsulation efficiency of drug in liposome as well as to enhance the stability of drug in liposomes. Such liposome is capable to increase the skin permeation of drugs. The preparation method comprises the following steps: (1) adding the drug to a Vitamin E derivative solution to form a mixture; and (2) adding at least one phosphatidyl choline to the mixture, after hydration from either sonication or homogenization. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008294340-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021234536-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013135892-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010039490-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9445975-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2978661-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012504620-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010039490-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112603850-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102170853-A |
| priorityDate |
2003-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |