| abstract |
The present invention provides a method for stimulating human leukocytes to kill microorganisms in biofilms. The invention also provides a methods, compositions and kits for treating or preventing a biofilm infection in a mammal comprising administering a therapeutically effective amount of a complement protein and one or more antibodies which bind to a bacterial, yeast, fungal, carbohydrate or lipid epitope present in the biofilm. Additionally, the invention provides methods, compositions and kits for treating biofilm infection in a mammal which comprises administering to the mammal a therapeutically effective amount of a complement protein and a conjugate composition. The invention also provides methods for determining Critical Neutrophil Concentration and Neutrophil Extraction Efficiency in a mammal. |