| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0bd02efd7e281c33c06a3f1d7bf0c51a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae66d46f5d0d859b1d30b5afe61b58ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9648ca3e2819c47ccf918b61076ad1c2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7b01ead21e06b707f194e12a0428a32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00db7acc7a7187e1d62430dd792d2dcc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2517-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2517-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-873 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-873
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-16 |
| filingDate |
2005-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d06b668c15c7879b058c35007733aab7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d0d45db213793371727f15c824b45b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b05d7ecae32790a24180c325ea184a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e8e45cd9acdc8e353a5e2ac674b164a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f8577c5483535e61ea8c5d0e3679cf3 |
| publicationDate |
2005-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005210537-A1 |
| titleOfInvention |
Pluripotent mammalian cells |
| abstract |
The invention relates to a method of making pluripotent stem cells that does not involve the formation of early preimplantation embryos or fetal tissue. The method has general utility in the production of pluripotent stem cells from many mammalian species but has particular application in man where pluripotent stem cell production can be customized to particular human individual. The method involves the fusion of donor somatic or stem cells (or their karyoplasts) with cytoplasmic, membrane-delimited fragments of mammalian oocytes or zygotes. After the initial genomic reprogramming occurs, the cells can proliferate and thus multiply in vitro yielding a large number of autologous cells for cell therapy application. The result of this process is a cell population genomically identical to the somatic, differentiated cells derived from an individual patient. However, these cells are pluripotent in that upon application of specific growth factors, the cells are capable of differentiating into specific cell types as required by the sought clinical indication. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11512283-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9834749-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10385312-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10968427-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9018010-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10876094-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9404079-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9410121-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9040297-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10066205-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8945925-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008050814-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008064098-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10590382-B2 |
| priorityDate |
2000-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |