| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3321a6fe54da532f6e0a63d9b509710b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9be2a04d148b4dd0d9e4b7a1bece4ac9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4bcd13eb61e3314f507f3c599dc3da6 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7076
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-655 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
2004-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ce6f390e229c224a097a5dd02490735
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72c53e54573bfd95097b6b63c76aa420
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08b32579853a994d2760087682797700 |
| publicationDate |
2005-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005209173-A1 |
| titleOfInvention |
Neurodegenerative protein aggregation inhibition methods and compounds |
| abstract |
Methods and compositions are provided for reducing aggregation of neurodegenerative proteins associated with neurotoxicity or other proteins. The compounds comprise a first domain or targeting element for binding to the target proteins linked to a second domain or recruiting element that binds to an aggregation inhibiting protein, e.g. a prolyl isomerase. By associating the aggregating forming proteins or neuronal cells under conditions where aggregating proteins are produced with the compound and the aggregation inhibiting protein, aggregation is reduced. The subject agents can be used in assays, investigating the etiology of the neuronal diseases and for prophylaxis and therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007054348-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009081641-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009082344-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017190016-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009083018-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009094003-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009055138-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008014572-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008015787-A1 |
| priorityDate |
2003-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |