http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005203074-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5685 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 |
filingDate | 2005-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40b6a28a47cb3cca65a17a93128c8322 |
publicationDate | 2005-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2005203074-A1 |
titleOfInvention | Modified aromatase inhibitors having improved bioavailability |
abstract | The present invention relates to the modification of 3-beta-hydroxyandrost-4-ene-6,17-dione (“3-OHAT”) and its metabolites/derivatives at either the 3 rd or 17 th carbon or 3 rd and 17 th carbons with various ethers and/or esters and to the modification of 3-beta-hydroxyandrost-4-ene-6,17-dione (“3-OHAT”) and its metabolites/derivatives at carbon 6 with a methyl, methoxy, methylene, hydroxymethylene or acetoxy functional group to improve and increase the oral bioavailability and/or plasma half life and/or efficacy in mammals. |
priorityDate | 2004-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 415.