Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
filingDate |
2005-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b6ea1bd184191902d1448bc9d5ec171 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0769d037f187159ae1f34e14d2e7eaf0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7848d654794919e212f0c56124b3d75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bcaf18ef1082946a06b93a04e7dc5e6 |
publicationDate |
2005-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2005197322-A1 |
titleOfInvention |
Compounds capable of binding to proteins constituting or associated with cytoskeletal elements, and their applications for the manufacture of medicaments |
abstract |
The invention concerns the use of steroids and non-toxic compounds, capable of crossing the blood brain barrier characterized in that they are capable of binding the same site as pregnenolone on proteins constituting or associated with elements of the cytoskeleton and of displacing the MAP 2 -bound pregnenolone, and of influencing the assembling and stabilization of microtubules. The invention is particularly useful for treating the nervous system, for fighting against ageing of cells containing MAP 5 , and for treating cancers. |
priorityDate |
2000-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |