| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-14222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-18122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-08 |
| filingDate |
2003-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1175696e0cb8c4c76b3310c39297fe2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d883dc3eaa20b6b8663a25fa14de8ddd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5da28987280f0fec48a6139623dbbe5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d7e9ed5f062eb97ac1a57922ebecf5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6883429502e39b92381a80ba239d0c71 |
| publicationDate |
2005-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005191628-A1 |
| titleOfInvention |
Antibiotics based upon bacteriophage lysis proteins |
| abstract |
This invention relates to polypeptide antibiotics, including materials and methods related thereto, based upon the observation that bacteriophage elaborate proteins that cause host cell lysis by interfering with specific steps in cell wall biosynthesis. Examples of antibiotics based upon this invention include the bacteriophage φX174 gene E product and structurally and/or functionally related polypeptide and small protein antibiotics that interact with MraY, and the bacteriophage Qβ gene A 2 product and structurally and/or functionally related polypeptide and small protein antibiotics that interact with MurA. This leads to the general model for obtaining new polypeptide antibiotics by using genetic approaches based on these findings to find polypeptide sequences which cause bacterial cell lysis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007044428-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007044428-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009053179-A1 |
| priorityDate |
1999-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |