| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-10001 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
| filingDate |
2004-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2712f204375773b36c8293c7c7717cb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_930d7edba2c62cb6576eb93fc744223f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aef72ff0d469517e06116ffb35dd602b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac4483b059852e11ae5434b857f8d74e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad53c30973107812d5e6e7b229fcd5dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a44b93358e6b8249befb827bdafdf496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd72611e8c2f601b56790675d5d3d6ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b333b5a8fe203a8df762ac28c18bc85 |
| publicationDate |
2005-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005181975-A1 |
| titleOfInvention |
Crystal structure of FMS-like tyrosine kinase |
| abstract |
The invention relates to FMS-like tyrosine kinase (FLT3), FLT3 binding pockets or FLT3-like binding pockets. The invention relates to a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. The invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. The invention relates to methods of using the structure coordinates to screen for and design compounds that bind to FMS-like tyrosine kinase protein, complexes of FMS-like tyrosine kinase protein, homologues thereof, or FLT-3-like protein or protein complexes. The invention also relates to crystallizable compositions and crystals comprising an FMS-like tyrosine kinase cytoplasmic domain or homologues thereof. The invention also relates to methods of identifying inhibitors of the cytoplasmic domain of FMS-like tyrosine kinase protein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7270987-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013288373-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7572614-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007202586-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009203045-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7892771-B2 |
| priorityDate |
2003-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |