http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005181495-A1

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filingDate 2005-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2005-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2005181495-A1
titleOfInvention Large scale productions of virus antigen
abstract The present invention provides improved methods of production of viral antigen on a culture of adherent cells bound to a microcarrier, wherein the methods provide for increased viral antigen yield per culture medium volume. The invention is also directed to a cell culture biomass of adherent cells having increased cell density and microcarrier concentration compared to the respective confluent cell culture.
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