http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005176092-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1003 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
filingDate | 2004-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f3384969bfc40262b88dddb6f588c3e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89a6bd3c75f8a15d3c46f3be16a162c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7837bca05de9aae553eb313030039b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5888770e1704023f3ffe4fa3938d24ab |
publicationDate | 2005-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2005176092-A1 |
titleOfInvention | Regulation of gene expression by protein methylation |
abstract | The invention relates to the cDNA and deduced amino acid sequence of the Coactivator Associated arginine (R) Methyltransferase protein, CARM1. A method is described for the use CARM1 to regulate gene expression in vivo. CARM1 has also been used to methylate arginine residues of histones, synthetic peptides, and other proteins. A method to use CARM1 to screen for drugs that inhibit its methyltransferase activity is also described, as is a method to screen for drugs that modulate CARM1's interactions with other proteins. |
priorityDate | 1998-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 558.