| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6636b59c3149a23a6ae7feaa3984d05f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57449
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57419
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57423
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57434 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-60 |
| filingDate |
2004-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_325320e3eb6c66a6bb247e66c8b31ee7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f5cdabdc843f331bb50e72810dd405f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c49890aaf91f9ca9f886a43f98db83d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_392e3fe916a8f4a7a6964382ce192f38 |
| publicationDate |
2005-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005170441-A1 |
| titleOfInvention |
Early detection of cancer of specific type using 1HNMR metabonomics |
| abstract |
A method for determining whether a patient has a particular type of cancer which comprises: a. obtaining an ascites, abnormal cell cellular fluid or serum sample from the patient; n b. diluting the sample with D 2 O; c. subjecting the sample to 1 HNMR to obtain a series of free induction decay outputs (FID's); d. mathematically modifying the data to obtain 1 HNMR spectra; e. correcting the 1 HNMR spectra for phase and baseline distortions; f. data reducing the corrected 1 HNMR spectra to obtain a plurality of integral spectral segments; g. compensating for effects of variation in suppression of water resonance; h. normalizing the resulting data to total spectral area to obtain normalized 1 HNMR spectra; i. subjecting the normalized 1 HNMR spectra to principal component analysis to obtain normalized data; and j. plotting and comparing the normalized data with corresponding control data indicating the presence of the particular type of cancer to determine whether the sample indicates that the patient has the particular type of cancer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8380445-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104615903-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007221835-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007055456-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014199228-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019008009-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010055690-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016051020-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011202285-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102339356-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10534001-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11096621-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107727680-A |
| priorityDate |
2003-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |