Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55544 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
filingDate |
2004-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_154de2f10d0244a9ec17a3001827ed94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4a725fe85b73a17c8b7bd27f6f839ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b942b927befb5423088e8fd1e6d1c7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43dd4832f8b8b221c45617fb1318824c |
publicationDate |
2005-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2005169848-A1 |
titleOfInvention |
Adjuvant activities of mutants of LT-Ila and LT-IIb enterotoxin lacking binding to ganglioside |
abstract |
The present invention describes the adjuvant activity of mutants of LT-IIa and LT-IIb enterotoxin which lack ganglioside binding activity. The adjuvant activity of the LT-IIb(T13I) mutant is comparable to that of the wild type LT-IIb. The adjuvant activity of LT-IIa(T34I) mutant is also described which exhibits a late onset adjuvant activity. These mutants are useful for enhancing immune response to antigens. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006182765-A1 |
priorityDate |
2003-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |