| abstract |
Compositions, use, article of manufacture and method for the treatment of a mammal infected with a virus of the Flaviviridae family are provided comprising administration to the infected mammal of a compound having the Formula I: n nwherein, n A is selected from: C 1 to C 6 alkyl and C 3 to C 6 cycloalkyl; and B is selected from: phenyl or thiazolyl, both of which optionally substituted with a group selected from NH(R 1 ) and NH(CO)R 1 , wherein R 1 is C 1 to C 6 alkyl; R is OH or a sulfonamide derivative; or a pharmaceutically acceptable salt thereof. |