abstract |
What is disclosed are growth hormone secretagogues, and their uses, of formula (I) wherein R1 is C 6 H 5 CH 2 OCH 2 —, C 6 H 5 (CH 2 ) 3 — or indol-3-ylmethyl; Y is pyrrolidin-1-yl, 4-C 1 -C 6 alkylpiperidin-1-yl or NR2R2; R2 are each independently a C 1 to C 6 alkyl; R3 is 2-napthyl or phenyl para-substituted by W; W is H, F, CF 3 , C 1 -C 6 alkoxy or phenyl; and R4 is H or CH 3 , or a pharmaceutically acceptable salt or solvate thereof. |