| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3425c4ec4507c9d893931783b923025b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-706
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0312 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0339 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-033 |
| filingDate |
2004-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a21981615d7316bc98e0db514016551a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e1f628aa2fb458a45a49608b8dca4fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0f762489c2f9ab308f94070fc53fcae |
| publicationDate |
2005-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005132421-A1 |
| titleOfInvention |
Transgenic flies expressing Abeta42-Arctic |
| abstract |
The present invention discloses a transgenic fly that expresses the Arctic mutant version of the human Aβ42 peptide of human amyloid-β precursor protein (APP), and a double transgenic fly that expresses both the Tau protein and the human Aβ42 Arctic peptide of human amyloid-β precursor protein (APP). The transgenic flies of the present invention provide for models of neurodegenerative disorders, such as Alzheimer's disease. The invention further discloses methods for identifying genetic modifiers, as well as screening methods to identify therapeutic compounds to treat neurodegenerative disorders using the transgenic flies. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112237170-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2977452-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008140449-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2550655-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2550655-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016051157-A1 |
| priorityDate |
2003-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |