http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005119336-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 |
| filingDate | 2004-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3151e6a7f81c178e50bc9aa2bbdf3930 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ceded95acb53d26c8ac4f0690e57d3d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cac4532525846bde30d46be6a82b5bf |
| publicationDate | 2005-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2005119336-A1 |
| titleOfInvention | Synthesis of derivatives of ginkgolide C |
| abstract | The subject invention provides ginkgolide C derivatives compounds having the structure: n nwherein R is H or -A-Ar, where A is an alkyl group; and n Ar is an aryl group, which may contain heteroatoms and may be unsubstituted or substituted by one to five substituents each selected from the group consisting of hydrogen, alkoxy, —CH 2 CO 2 R 4 , and —CH 2 CONR 5 R 6 ; n where R 4 is an alkyl group; and R 5 and R 6 are each, independently, hydrogen or a branched or unbranched alkyl group; n wherein R 1 is H or —COR 7 , n where R 7 is alkyl, aryl or amino; n wherein R 2 is present or absent, and when present is H, —COR 8 or —CO-Z-R 8 ; n where R 8 is alkyl, aryl or amino; and Z is oxygen; n wherein R 3 is present or absent, and when present is —COR 9 ; n where R 9 is alkyl or aryl; n wherein only one of R 2 or R 3 is present in the compound; wherein only two of R, R 1 , R 2 and R 3 are H; and wherein each of a and b designates a single covalent bond which is present or absent, n where bond a is present when R 3 is absent and bond b is present when R 2 is absent; or an optically pure enantiomer of the compound. Additionally, the subject invention provides methods of inhibiting the activity of a glycine receptor using these compounds. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008306145-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7763741-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003231546-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7473788-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007098632-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009221019-A1 |
| priorityDate | 2003-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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