| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f07ba5e7ff356b7eda43fdfc20eef4b0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-14222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-6072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-6081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-609
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-13045 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2004-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_687f564bfd0c1927efcb16167b05f9d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f21f2b60963633c82918879cfe218ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e116e8eadec06d02e27f678e3631efd4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e0ef6a5559adcb721c3c1ec1e4a84e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f61ce7480ab182e56833379424015ba |
| publicationDate |
2005-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005112098-A1 |
| titleOfInvention |
Pseudotyped viruses and methods for their use |
| abstract |
The invention provides a method to introduce a selected nucleic acid sequence into an airway epithelial cell that involves contacting the airway epithelial cell with a pseudotyped retrovirus that includes a glycoprotein in which a portion of an O-glycosylation region within the glycoprotein has been deleted and a retroviral capsid that includes the selected nucleic acid sequence. The invention also provides a method to reduce or eliminate the symptoms of cystic fibrosis in a mammal that involves contacting an airway epithelial cell of the mammal with a pseudotyped retrovirus that includes a glycoprotein in which a portion of an O-glycosylation region within the glycoprotein has been deleted and a retroviral capsid that includes a nucleic acid sequence that encodes a cystic fibrosis transmembrane regulator protein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009118212-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005100890-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8887713-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010076061-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006093590-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7981656-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010074911-A1 |
| priorityDate |
2001-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |