Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_768e5b2a87837ff0f585625018568a8c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7151 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 |
filingDate |
2002-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ee67d5d61c79ed59dc9d8573d09d89e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a62e1c16f97ae667ac350f926999a1f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77b880e542c979d89337051132ee3674 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0cb9147e9256f8acf237f5eec95ec68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8da3b749b519572697d474ffd5c035ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2ab3e47f4198cad67ddc80b4dab747a |
publicationDate |
2005-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2005100547-A1 |
titleOfInvention |
Sphingosine kinase interacts with traf2 and modulates tumor necrosis factor-induced cellular activity |
abstract |
The present invention relates generally to a method of modulating cytokine-mediated cellular activity and to agents useful for same. More particularly, the present invention contemplates a method of modulating tumor necrosis factor-mediated cellular activity by modulating an intracellular sphingosine kinase-dependent signalling mechanism. The method of the present invention is useful, inter alia, in the treatment and/or prophylaxis of conditions characterised by aberrant, unwanted or otherwise inappropriate cytokine-mediated cellular activity The present invention is further directed to methods for identifying and/or designing agents capable of modulating the subject sphingosine kinase-dependent signalling mechanism. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006270630-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8324237-B2 |
priorityDate |
2001-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |