abstract |
The present invention relates to compositions, including pharmaceutical compositions that inhibit complement activation, and contain amino acid sequences X 1 -X 2 -X 3 -W-E-X 4 -X 5 -X 6 and/or Z 1 -C 1 -Z 2 -P-Z 3 -Z 4 -C 2 -Z 5 as described. The invention further relates to methods of inhibiting complement activation in vivo or ex vivo by administering a pharmaceutical composition as described herein. |