| abstract |
System and method for correcting spectral skew in a mass spectrometer by optimizing the mass spectrometer for a mass spectrometry performance parameter, generating measured spectra of a known reference compound, comparing the measured spectra to the known spectra of the known reference compound, generating a correction function from the comparison, and using the correction function to correct subsequent scans on the mass spectrometer. The present invention involves the use of a software correction of spectra (signal processing) to match any reference mass spectral response paradigm (e.g., magnetic sector instruments). By applying a software correction, the performance of the mass spectrometer may then be optimized independently, thereby yielding better overall performance of the system. |