| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6929 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
2002-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae154d11d10c69512673ace2b31db835
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85ff1e0ec319cea64da51e30b79ec228
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4146bcb718ba1f7aaa27b014398bee0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51b3242423e7c0de4b3d9966b1d873fc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_652a0d6c93516c38fde5df0601c4a9a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e61b5a5ebcbc439959e9cca22e6f2392
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62e320a4c31f4ecb13f3fc3932eae36e |
| publicationDate |
2005-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005079222-A1 |
| titleOfInvention |
Production of nanoparticles from methyl vinyl ether and maleic anhydride for the administration of hydrophilic pharmaceuticals, more particularly of puric and pyrimidinic bases |
| abstract |
Manufacture of nanoparticles on the basis of methyl vinyl ether and maleic acid for the administration of pharmaceuticals of an hydrophilic nature, in particular analogs of puric and pyrimidinic bases. The nanoparticles are obtained by desolvation with an hydroalcoholic phase of a methyl vinyl ether and maleic acid copolymer solution in acetone. The particles obtained are next treated with cross-linking agents (diamines or proteins) for the purpose of prolonging their useful life and are, possibly, incubated with a pharmaceutical which will be transported on the surface. The nanoparticles can carry the pharmaceutical likewise encapsulated which would then be added during the desolvation. In the case of the nanoparticle-ligand conjugates, the nanoparticles previously obtained and containing inside the pharmaceutical to be transported are incubated with the ligand or molecule which will contribute the property of specifically recognising a particular receptor of the organism. These pharmaceutical forms have as objective to improve the transport of the pharmaceutical or biologically active molecule to its site of action and/or absorption. This property improves the specificity and effectiveness of said pharmaceuticals. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10005930-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10526458-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10767099-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017048719-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010524902-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007224225-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8628801-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013004651-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8895067-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9351940-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10160902-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008248125-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2628881-C2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10351752-B2 |
| priorityDate |
2001-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |