Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_278b17160b53bb5899ea82e0d4106fd1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10332 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-108 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 |
filingDate |
2004-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0a49273f221f8519c6fb4187809d35b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f670a502626922998901a86982c4f6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d95d7da4becba591acc9564e2f028f3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adaf22bcd540f192848c61ba619ce32e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_032af2cc422bab7f45f6920efb7ff2a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d2963e5c27fef6dc797f3e30a6ee5f6 |
publicationDate |
2005-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2005079158-A1 |
titleOfInvention |
Construct of anti-cancer recombinant adenovirus, method for preparing the same and use thereof |
abstract |
Disclosed is a recombinant human adenovirus type 5 adenovirus construct, in which a fragment in the E1A region of the ADV5 genome and a fragment in the E3 region are deleted while a foreign cDNA fragment is reversely inserted into the deleted E3 region. A method for preparing the recombinant ADV5 construct is also provided. The construct provided herein presents a tumor-specific replication, tumor-specific expression of the inserted anti-gene and tumor-specific bystander effects, and is suitable for use in tumor therapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010166799-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11077156-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11401529-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018169271-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11130968-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9345787-B2 |
priorityDate |
2003-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |