http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005075483-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69108fc12b940ede105638f37f06080b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-19 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-047 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-50 |
| filingDate | 2003-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_500d2128e7b389d4b9cc770e441f6385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d256a3f3fe5bb3b06d03ef59c19267da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fd3be72dae6588f0e1018841b7d3472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b6ba79b681a0ee41d4920924db7bdeb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ff2e498ffd0143cc4014c04900481ad |
| publicationDate | 2005-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2005075483-A1 |
| titleOfInvention | Glycopeptide antibiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same |
| abstract | A glycopeptide of the formula A 1 -A 2 -A 3 -A 4 -A 5 -A 6 -A 7 , in which each dash represents a covalent bond; wherein A 1 comprises a modified or unmodified α-amino acid residue, alkyl, aryl, aralkyl, alkanoyl, aroyl, aralkanoyl, heterocyclic, heterocyclic-carbonyl, heterocyclic-alkyl, heterocyclic-alkyl-carbonyl, alkylsulfonyl, arylsulfonyl, guanidinyl, carbamoyl, or xanthyl; wherein each of A 2 to A 7 comprises a modified or unmodified α-amino acid residue, whereby (i) A 1 is linked to an amino group on A 2 , (ii) each of A 2 , A 4 and A 6 bears an aromatic side chain, which aromatic side chains are cross-linked together by two or more covalent bonds, and (iii) A 7 bears a terminal carboxyl, ester, amide, or N-substituted amide group; n and wherein one or more of A 1 to A 7 is linked via a glycosidic bond to one or more glycosidic groups each having one or more sugar residues, at least one of the sugar residues bearing one or more substituents of the formula YXR, N + (R 1 )═CR 2 R 3 , N═PR 1 R 2 R 3 , N + R 1 R 2 R 3 or P + R 1 R 2 R 3 in which Y is a single bond, O, NR 1 or S; X is O, NR 1 , S, SO 2 , C(O)O, C(O)S, C(S)O, C(S)S, C(NR 1 )O, C(O)NR 1 , or halo (in which case Y and R are absent). A chemical library comprising a plurality of the glycopeptides of the invention. A method for preparing a glycopeptide by glycosylation of an aglycone derived from a glycopeptide antibiotic. A method for preparing a glycopeptide by preparing a pseudoaglycone from a glycopeptide antibiotic and glycosylating the pseudoaglycone. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008140973-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010105607-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011015119-A1 |
| priorityDate | 1998-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 794.