| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1086
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-80 |
| filingDate |
2004-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_559ead4d9ba6cb9b56ae7c93fe2d359e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_166b51c9fc4b5cacc32dbc35736a648e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7d713337edeb712a00792fb0727bde9 |
| publicationDate |
2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005070016-A1 |
| titleOfInvention |
RNA-based transcriptional regulators |
| abstract |
RNA molecules have been shown to play a variety of functional roles in biological processes. RNA sequences can adopt 3-D conformations able to regulate transcription. RNA-based transcriptional regulators when recruited to a DNA template act to promote or suppress the transcription of nearby genes. The regulators are thought to act by mimicing the activation domains of protein transcriptional activators. These RNA-based transcriptional regulators may be engineered to regulate transcription based on the binding of a ligand such as a small molecule. RNA sequences of the regulators may be evolved to produce regulators with a greater degree of transcriptional activation or suppression. The RNA-based system of the present invention is useful in studying biological processes and in altering biological process in a therapeutic context. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8395023-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019209975-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110582571-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9212370-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007089186-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9000264-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006200878-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008156987-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009013434-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10435686-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10793869-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010305197-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9708620-B2 |
| priorityDate |
2003-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |