| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91045 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2002-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bceaaed4f215b37b516291361f43065d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_732e243917cd851420a73cb348272e82 |
| publicationDate |
2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2005069986-A1 |
| titleOfInvention |
P300 histone acetylase inhibitor |
| abstract |
An inhibitor of histone acetyltransferase p300 was isolated from human cDNA library and identified as a nuclear protein composed of 855 amino acid residues. It binds to the cysteine/histidine-rich region of p300, thereby inhibiting the transcriptional activation by p300. It also inhibits the transcription activity of p53, with p300 functioning as a coactivator, and inhibits the discontinuance of cell cycle that relies on p53. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008145928-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8889408-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1541685-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1541685-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009046483-A1 |
| priorityDate |
2001-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |