http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005065063-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-54 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96 |
| filingDate | 2002-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da64094ce5bd045a95ee03071ef08502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c421575d8f9b9cfe44e8119d7af1d210 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95179825a4a78ddca3d74a57e07dc078 |
| publicationDate | 2005-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2005065063-A1 |
| titleOfInvention | Supercritical fluids processing: preparation of protein microparticles and their stabilisation |
| abstract | A process for the co-precipitation of a substance with a stabiliser therefor, by a gas anti solvent process compris- ing introducing into a particle formation vessel a supercritical fluid pure or mixed with a modifier, and a solution comprising said substance and said stabiliser dissolved in a solvent; so as said solvent is extracted from the solution by said supercritical fluid and co-precipitation of the substance and stabiliser occurs. The process may be carried out using an apparatus comprising a particle formation vessel ( 22 ) and a nozzle ( 27 ) having a central orifice ( 39 ) serving to introduce a solution of the substance and a plurality of outer orifices ( 41 ) serving to carry a flow of supercritical fluid into the particle formation vessel ( 22 ), such that the solvent is extracted from the solution by the supercritical fluid and precipitation of micron sized particles of the substance/stabilizer occurs. The substance is preferably a protein of pharmaceutical interest, which is highly stabilized for storage by this process. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018020551-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110055238-A |
| priorityDate | 2001-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 328.