abstract |
A medicinal aerosol product comprising a pressurized metered dose inhaler, including a canister ( 1 ) equipped with a metering valve and containing a medicinal aerosol solution formulation, and an actuator ( 2 ) comprising a nozzle block ( 14 ) defining an actuator orifice ( 6 ) leading to an expansion chamber, wherein the formulation includes a cannabinoid, a hydrofluorocarbon propellant and an optional amount of an alcohol co-solvent, and the actuator orifice ( 6 ) has a diameter of about 0.30 mm or less, and/or is laser drilled. |