http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005059603-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6475 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
filingDate | 2003-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e3bff4325fdd1c78488c05e7b0d5aa9 |
publicationDate | 2005-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2005059603-A1 |
titleOfInvention | Compounds which prevent neuronal cell death and uses thereof |
abstract | The present invention provides for a compound having the structure: (AA 1 ) n -Cys-(AA 2 ) m wherein n=0,1,2,3,4 or 5 and m=0,1,2,3,4 or 5, provided the sum of (n+m) is greater than or equal to two and less than or equal to five, if n=1, (AA 1 )=Ala-, if n=2, (AA 1 ) n =Gln-Ala-, if n≧3, (AA 1 ) n =(Xaa) p -Gln-Ala-,and Xaa=any amino acid and wherein if n=n3, p=1, if n=4, p=2, if n=5, p=3, if m=1, (AA 2 ) m =-Arg, if m=2, (AA 2 ) m =-Arg-Gly, if m≧3, (AA 2 ) m =-Arg-Gly-(Xaa) q , wherein if m=3, q=1, if m=4, q=2, if m=5, q=3. The present invention provides for a method of inhibiting cell death and a method for alleviating symptoms of a neurodegenerative disorder in a subject. |
priorityDate | 1996-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 351.