Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f62dc59e99eec0989a8b52a43bad4b9d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 |
filingDate |
2003-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc261ea9289bef481a4660719862c57c |
publicationDate |
2005-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2005053591-A1 |
titleOfInvention |
Compositions and uses of motor protein-binding moieties |
abstract |
The invention provides methods and reagents for efficient transport of macromolecules (such as drug therapeutics including nucleic acids and polypeptides) linked to motor protein-binding moieties (MPBM) intracellularly to a specific subcellular localization. One exemplary MPBP is dynein binding moiety (DBM). Drug therapeutics linked to DBM can be selectively, specifically, and actively transported intracellularly to the nucleus or peri-nuclear region, thus enhancing the uptake of such drug therapeutics into the target subcellular localization. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11008568-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11008383-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9464286-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10377813-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10196635-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010021912-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010119528-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10072065-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8435790-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9766248-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11186845-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10329555-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10189894-B2 |
priorityDate |
2002-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |