Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59e1d955a7b1560dc68cf7fd800e8fac |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70567 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
filingDate |
2004-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db7196aefb103f136621894bd060ae9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4c3b0a86eafc752ac85662b39115834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d38e520e1a47974a218d4b58dcfb852 |
publicationDate |
2005-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2005042730-A1 |
titleOfInvention |
Gene screening method using nuclear receptor |
abstract |
A system in which a ligand is formed by the expression of a polypeptide that converts a ligand precursor into a ligand, and the ligand thus formed binds to a nuclear receptor to thereby induce the expression of a reporter gene located downstream of the target sequence is constructed. Searching a gene library using this system can isolate a gene encoding a polypeptide capable of converting a ligand precursor into a ligand. This system, which takes the advantage of the transcriptional regulatory function of a nuclear receptor, enables screening a ligand that binds to a nuclear receptor and to examine whether or not a test compound is a ligand that binds to the nuclear receptor, and also screening genes that encode polypeptides capable of converting an inactive form of a wide range of transcriptional regulatory factors into an active form. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7288407-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8030016-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006105417-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010068707-A1 |
priorityDate |
1997-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |