Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a82871cd2126b7cfd25f59e9ed692d8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2510-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2004-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac1d9621d9558abb038b051b86b6ace1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da839e8e5243bec2ac403089b57967cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05899ffec968eb2093e9b86e5f3ae9bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68c93ce6c8f1d2e8a6b8b1fdbbcf61d3 |
publicationDate |
2005-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2005042643-A1 |
titleOfInvention |
Elavl-1 |
abstract |
The invention provides a method for detecting apoptosis in a cell comprising detecting a decrease in any one of: i) an ELAVL-1 (embryonic lethal, abnormal vision, Drosophila-like 1) polypeptide having an amino acid sequences as set out in SEQ ID NO: 1; ii) a polypeptide having at least 80% homology with i); iii) a nucleic acid encoding a polypeptide having the sequence set out in i) or ii); iv) a nucleic acid which hybridises under stringent conditions to the sequence set out in iii); or v) the complement of iii) or iv). The invention accordingly provides a method of modulating apoptosis by modulating ELAVL-1 gene expression and a method for identifying genes associated with ELAVL-1 gene expression and thus identifying other genes associated with apoptosis. The invention also provides a novel nucleic acid sequence encoding the promoter region for ELAVL-1. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9969801-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011110896-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9188580-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009136947-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8759091-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8426123-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008138818-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011189658-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009162889-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011044504-A1 |
priorityDate |
2001-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |