| abstract |
The present invention relates to an improved process for determining γ-secretase activity and for detecting γ-secretase, a subunit protein of γ-secretase, or a γ-secretase-like proteinase; particular embodiments of the process relate on the one hand to processes for the identification of a γ-secretase or of a cDNA which codes for a γ-secretase, a subunit protein of γ-secretase, or a γ-secretase-like proteinase, and on the other hand to processes for the identification of substances which can inhibit the activity of a γ-secretase, a subunit protein of γ-secretase, or a γ-secretase-like proteinase. |