http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005026859-A1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate | 2003-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_805efa1a6a2da43eb5fb1fa930612a89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e8bbbc7a710d9c6110aa4061669cb87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_776011898a8feb21fa2eea5c0194ddd7 |
| publicationDate | 2005-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2005026859-A1 |
| titleOfInvention | Methods and compositions of gene delivery agents for systemic and local therapy |
| abstract | A method is provided for the packaging of a nucleic acid with a chelating agent having a coordinating moiety linked to a central hydrophobic moiety that terminates in a hydrophilic moiety. The complex is well suited for oral and other forms of therapeutic administration of nucleic acids in order to exact systemic and/or localized gene delivery therapy. Intestinal epithelial cells, as well as non-epithelial cells within the gastrointestinal tract and other target cells, are transformed for short or long-term therapies through oral administration, direct injection, or infusive administrations. A nucleic acid conjugating agent particulate composition amenable for administration as a gene therapy composition is provided. The composition is readily adjusted to create a particle having a controlled size and net-zero, -positive, or -negative charge. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114917215-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011218156-A1 |
| priorityDate | 2002-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1917.