| abstract |
A compound of the formula n nwherein n R 1 is: n n R 5 is: n n nand n, m, Z, R 8 , R 9 , R 10 and R 11 are as defined herein, useful in the treatment of diabetes, insulin resistance, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, cataracts, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemia, hyperlipidemia, atherosclerosis, and tissue ischemia, particularly, myocardial ischemia. |