http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005014135-A1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-553 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-55 |
filingDate | 2004-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61992b18d9b815d5785049d395d2d164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81bd44df5e4198200764facc5f020e6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a89dba66e8cbc94fda86db17f58eb1e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43dfe18971c2a044b487cf07bc88d4cb |
publicationDate | 2005-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2005014135-A1 |
titleOfInvention | Method for the selection and identification of peptide or protein molecules by means of phage display |
abstract | The invention relates to a method for the selection and identification of at least on representative (interaction partner) from a plurality of peptide or protein molecules, which can specifically interact with at least one representative from a plurality of target molecules, forming a bond. The inventive method comprises the following steps: (a) a virus system consisting of a plurality of viruses, wherein each virus respectively presents at least on representative from the plurality of peptide or protein molecules on the surface thereof, is brought into contact with the plurality of target molecules (ligands) which are immobilized on the surface of a solid phase carrier such that they are position addressable in a two-dimensional grade; (b) unbound viruses removed from the surface thereof; and (c) the interaction partner is identified by detection and determination of the position of the bond between the immobilized ligand and the interaction partner presented by the virus with the aid of a marker-free detection method. The described method makes it possible to concentrate viruses presenting interaction partners by means of an optionally cyclic repetition of selection. Optionally, selected interaction partners are recombinantly expressed after identification of the coding nucleotide sequence. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006141611-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008213481-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9562266-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7629173-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7851208-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006141527-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006139641-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7604984-B2 |
priorityDate | 2001-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 193.