| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb9c6b40161bafe7bd55f0b4defcea04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C253-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-08 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-58 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C6-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-95 |
| filingDate |
2004-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_649da3ead44d8ac76cbff0c1665798d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21818cfafb6897aeb162808e33392b0b |
| publicationDate |
2004-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2004267011-A1 |
| titleOfInvention |
Methods for synthesis of diarylmethanes |
| abstract |
The present invention relates to dihydrofolate reductase inhibitors having an aromatic group and a heteroaromatic group linked by a methylene group; methods of preparation of dihydrofolate reductase inhibitors that include metal mediated cross coupling of an aromatic halide or heteroaromatic halide with an organozinc reagent; and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such dihydrofolate reductase inhibitors. |
| priorityDate |
2001-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |